Skip to content
ClinCalc Pro
Menu
Calculators Drugs Pathways AI Dx Donate Get the App
Cardiology Infectious Disease

IE 6-Month Mortality Risk Score (ICE)

Predicts 6-month mortality in definite infective endocarditis from host factors, IE characteristics, complications and surgical treatment (International Collaboration on Endocarditis).

Score interpretation

Score ≤ 6 — 6-Month Mortality ~10 % -5–6

Lowest risk quintile: 6-month mortality 10.3 % (ICE-PLUS validation).

→ Standard IE management with the endocarditis team.

Score 7–8 — 6-Month Mortality ~17 % 7–8

6-month mortality 17.0 % (ICE-PLUS validation).

→ Endocarditis team review; reassess complications and surgical indications.

Score 9–10 — 6-Month Mortality ~26 % 9–10

6-month mortality 25.5 % (ICE-PLUS validation).

→ Endocarditis team review; reassess complications and surgical indications.

Score 11–16 — 6-Month Mortality ~38 % 11–16

6-month mortality 37.8 % (ICE-PLUS validation).

→ High risk: urgent endocarditis team and cardiac surgical review.

Score ≥ 17 — 6-Month Mortality ~53 % 17–26

Highest risk quintile: 6-month mortality 52.9 % (ICE-PLUS validation).

→ Very high risk: urgent endocarditis team and cardiac surgical review; discuss goals of care.

Interpretation bands for the IE Mortality. Apply clinical judgement and local guidance.

References

Related

Curated clinical cross-links plus same-class fallbacks.

Calculators
Drugs
Pathways

Decision support only — verify against a current formulary, NICE, or your local guideline before clinical use.