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Endocrinology General Medicine Emergency Medicine Standard pharmacological equivalence

Steroid Dose Equivalence

Converts corticosteroid doses to prednisolone equivalent. Useful for switching steroids or assessing adrenal suppression risk.

Score interpretation

Physiological / Low 0–7.4

Prednisolone equivalent ≤7.5 mg/day: Physiological or low dose. Low adrenal suppression risk.

→ Low-dose: limited systemic side effects. Consider bone protection if long-term (>3 months).

Moderate Dose 7.5–29.9

Prednisolone equivalent 7.5–30 mg/day: Moderate dose. Significant immunosuppression.

→ Bone protection (calcium/vitamin D ± bisphosphonate). Blood glucose monitoring. Stress dosing instructions for illness.

High Dose ≥ 30

Prednisolone equivalent ≥30 mg/day: High-dose steroids. High risk of adrenal suppression and Cushing's effects.

→ PCP prophylaxis (if >4 weeks). Bone protection. Do NOT stop abruptly. Endocrinology advice for weaning if long course.

Interpretation bands for the Steroid Equiv.. Apply clinical judgement and local guidance.

References

Related

Curated clinical cross-links plus same-class fallbacks.

Decision support only — verify against a current formulary, NICE, or your local guideline before clinical use.