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Paediatrics Anaesthesia & Critical Care Respiratory

Oxygenation Index (OI)

Calculates the Oxygenation Index (OI) for mechanically ventilated children. Under PALICC-2 (2023), the oxygenation criterion for paediatric ARDS (PARDS) with invasive ventilation is OI ≥ 4 or OSI ≥ 5. Severity, applied ≥ 4 h after initial diagnosis: mild/moderate OI < 16, severe OI ≥ 16 (or OSI ≥ 12). PARDS also needs the other PALICC-2 criteria.

Score interpretation

Below the OI Threshold for PARDS (OI < 4) 0–3.99

→ OI < 4 does not meet the OI arm of the PALICC-2 oxygenation criterion for paediatric ARDS with invasive ventilation (OI ≥ 4 or OSI ≥ 5); check the OSI.

Mild/Moderate PARDS (OI 4 to < 16) 4–15.99

→ PALICC-2: with invasive ventilation, OI ≥ 4 meets the PARDS oxygenation criterion; severity, applied ≥ 4 h after initial diagnosis, is mild/moderate at OI < 16. PARDS also needs the other PALICC-2 criteria. Lung-protective ventilation; PEEP optimisation; PICU level care.

Severe PARDS (OI ≥ 16) ≥ 16

→ Severe PARDS at OI ≥ 16 (PALICC-2, applied ≥ 4 h after initial diagnosis). Escalate to PICU; consider prone positioning. ECMO: PALICC-2 sets no strict criteria — consider it when lung-protective strategies fail and the cause is reversible.

Interpretation bands for the Oxygenation Index. Apply clinical judgement and local guidance.

References

Related

Curated clinical cross-links plus same-class fallbacks.

Decision support only — verify against a current formulary, NICE, or your local guideline before clinical use.