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Topical psoriasis preparation

Coal tar with zinc oxide

Brand names: Carbo-Dome

A topical preparation combining coal tar with zinc oxide, used for chronic inflammatory and scaling skin conditions such as psoriasis and eczema, where zinc oxide provides a soothing, protective barrier alongside the antiscaling action of tar.

Dosing — being independently re-sourced

ClinCalc Pro is rebuilding its dose data from primary open sources — the manufacturer SmPC (eMC), the WHO Model Formulary and other official references — under clinician review. This drug's structured dose is not yet published here. Confirm all doses against the product SmPC and your local formulary before prescribing.

Clinical monograph

How it works

Coal tar provides anti-inflammatory, antiscaling and antipruritic effects on the skin, while zinc oxide acts as a mild astringent and protective barrier that soothes irritation and helps shield the skin.

Prescribing in practice

  • Coal tar increases sensitivity to ultraviolet light, so treated skin should be protected from sunlight and caution applied if phototherapy is used.
  • Avoid application to broken, infected or acutely inflamed skin, where tar may cause irritation or folliculitis.
  • The preparation stains skin, hair, clothing and bedding and has a tar odour.

Monitoring

No laboratory monitoring is required; review the skin clinically for irritation and response to treatment.

Counselling the patient

  • Apply as directed; expect staining of fabrics and a characteristic smell.
  • Keep treated skin out of strong sunlight.
  • Stop if the skin becomes sore, spotty or irritated and seek advice.

Evidence & guidelines

Coal tar with zinc oxide is an established topical preparation for chronic plaque psoriasis and eczema, used within stepped topical regimens recommended by NICE.

Reference: Drug verified in RxNorm (NLM); confirm dosing against the manufacturer SPC (eMC). Verify against your local formulary and current prescribing references before prescribing. Monograph status: clinician-reviewed (2026-07-04).

Related

Curated clinical cross-links plus same-class fallbacks.