NeurologyInfectious Disease
Encephalitis (Viral + Autoimmune)
Empirical aciclovir, autoimmune workup (anti-NMDA, LGI1, etc.), MRI, EEG, ITU monitoring, immunotherapy.
Source: ABN 2012; IDSA
Used in: Meningitis & Encephalitis
Step 1 of ~7
info
Recognise
Subacute alteration in consciousness/personality/cognition + ≥2 of: fever, seizures, focal neurology, CSF pleocytosis, EEG/imaging changes. Differentials: meningitis (more headache + neck stiffness), brain abscess, malignancy, vasculitis, toxic-metabolic encephalopathy (drugs, electrolytes, hepatic, uraemic).
Related
Curated clinical cross-links plus same-class fallbacks.
Drugs
- Lecanemab (Anti-Amyloid Monoclonal Antibody) · Anti-Amyloid Immunotherapy (IgG1 Monoclonal Antibody)
- Donanemab (Anti-Amyloid Monoclonal Antibody) · Anti-Amyloid Immunotherapy (IgG1 — Targets Pyroglutamate-Modified Amyloid-β)
- Amantadine · Dopamine Agonist / NMDA Antagonist (Anti-Parkinsonian)
- Aciclovir (Paediatric) · Antiviral — HSV Encephalitis / Neonatal Herpes / VZV in Immunocompromised
- Ketamine (Anaesthesia/Sedation) · Dissociative Anaesthetic (NMDA Receptor Antagonist)
- Trimetazidine · Metabolic Anti-Anginal
Pathways
- Acute Stroke / TIA Assessment · NICE NG128; RCP Stroke Guidelines 2023
- Status Epilepticus (Adults) · NICE CG137; ESEM guidelines; RCP Neurology Guidelines
- Suspected Subarachnoid Haemorrhage · NICE NG228; RCEM 2023; AHA/ASA 2023
- Adult Head Injury · NICE NG232 (2023)
- Bell's Palsy / Facial Nerve Palsy · ENT UK 2017; AAN
- Vertigo Workup · ENT UK; NICE CKS
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