CHARGE-AF Score for Incident Atrial Fibrillation
Cohort for Heart and Aging Research in Genomic Epidemiology (CHARGE) AF score. Predicts 5-year risk of developing new-onset atrial fibrillation in patients in sinus rhythm.
Score interpretation
→ CHARGE-AF Low Risk: <5% 5-year AF risk. Optimise cardiovascular risk factors; lifestyle advice (weight reduction, alcohol reduction, exercise); reassess annually.
→ CHARGE-AF Intermediate Risk: 5–10% 5-year AF risk. Consider implantable loop recorder or Holter monitoring if symptomatic palpitations; aggressive risk factor modification; BP control to <130/80 mmHg; weight loss.
→ CHARGE-AF High Risk: >10% 5-year AF risk. Discuss stroke prevention planning; wearable or prolonged ECG monitoring; consider prophylactic anticoagulation if AF detected; aggressive risk factor management (hypertension, sleep apnoea, obesity, alcohol).
Interpretation bands for the CHARGE-AF Score. Apply clinical judgement and local guidance.
References
Related
Curated clinical cross-links plus same-class fallbacks.
- CHA₂DS₂-VASc Score · Atrial Fibrillation
- ORBIT Bleeding Risk Score for AF · Atrial Fibrillation
- CHA₂DS₂-VA Score for AF (2023) · Atrial Fibrillation
- CHADS-65 for Atrial Fibrillation · Atrial Fibrillation
- GARFIELD-AF Risk Score for Atrial Fibrillation · Atrial Fibrillation
- CHADS-65 Score for Atrial Fibrillation · Atrial Fibrillation
- Vernakalant · Atrial-selective antiarrhythmic
- Sodium Chloride 0.9% Nasal Irrigation / Spray · Nasal irrigation / saline decongestant (non-pharmacological adjunct)
- Palivizumab · RSV Prophylaxis — Monthly Monoclonal Antibody (High-Risk Infants)
- Ziprasidone · Atypical Antipsychotic — D2/5-HT2A Antagonist (Low Metabolic Risk)
- Atorvastatin (CKD Cardiovascular Risk) · Cardiovascular Risk in CKD
- Diclofenac potassium · NSAID (rapid-onset salt)
- Acute Heart Failure · ESC 2021 Heart Failure Guidelines; NICE NG106
- NSTEMI / Unstable Angina · ESC 2020 NSTEMI Guidelines; NICE NG185
- New-Onset Atrial Fibrillation · ESC 2020 AF Guidelines; NICE NG196
- Hypertensive Emergency · ESC/ESH 2018 Hypertension Guidelines; NICE NG136
- Bradycardia Management · Resuscitation Council UK ABCDE; ESC 2021 Pacing Guidelines
- Ventricular Tachycardia / Fibrillation · Resuscitation Council UK ACLS; ESC 2022 Ventricular Arrhythmia Guidelines
Decision support only — verify against a current formulary, NICE, or your local guideline before clinical use.