Antacid

Magnesium trisilicate

Magnesium trisilicate is a magnesium-containing antacid used for the symptomatic relief of dyspepsia and heartburn, commonly formulated with other antacids.

Dosing — no UK product information found

We found no UK product information (SmPC) for this medicine or presentation on the eMC or MHRA Products (checked October 2026). It may be unlicensed in the UK, imported, a medical device, or no longer marketed. ClinCalc Pro shows only doses it can trace to official product information, so none is shown — follow your specialist service or local guideline.

Clinical monograph

How it works

It neutralises gastric acid and reacts with it to form silica gel, which can provide a degree of mucosal protection.

Prescribing in practice

Magnesium salts may accumulate in renal impairment, so use with caution and avoid in significant renal failure.
As a magnesium-based antacid it tends to have a laxative effect and is often combined with constipating aluminium salts.
Antacids can interfere with the absorption of other medicines, so separate dosing from interacting drugs.

Monitoring

Routine monitoring is not required for occasional use, but consider renal function in patients with impairment or regular magnesium-containing antacid use.

Counselling the patient

Take it for symptom relief and space it apart from your other medicines.
Tell your clinician if you have kidney problems or if indigestion does not settle.

Evidence & guidelines

Antacids such as magnesium trisilicate are an established option for the symptomatic relief of dyspepsia in line with NICE guidance.

Reference: Drug verified in RxNorm (NLM); confirm dosing against the manufacturer SPC (eMC). Verify against your local formulary and current prescribing references before prescribing. Monograph status: clinician-reviewed (2026-07-04).

Curated clinical cross-links plus same-class fallbacks.

Calculators

Pediatric Asthma Severity Score (PASS) · Asthma

Drugs

Pathways