infectious-disease
HIV Incidence Risk Index for MSM (HIRI-MSM)
Validated risk score identifying HIV-negative men who have sex with men (MSM) at highest risk for HIV acquisition who would benefit most from pre-exposure prophylaxis (PrEP). Derived from the EXPLORE cohort. Score 0–45; score ≥11 indicates high risk warranting PrEP discussion.
References
- Smith DK et al. Vital Signs: Estimated Percentages and Numbers of Adults with Indications for Preexposure Prophylaxis to Prevent HIV Acquisition — United States, 2015. MMWR. 2015;64(46):1291–1295.
- Menza TW et al. Predicting human immunodeficiency virus acquisition among men who have sex with men. Sex Transm Dis. 2009;36(9):547–555.
Related
Curated clinical cross-links plus same-class fallbacks.
Drugs
- Propranolol (Migraine Prevention) · Beta-Blocker — Migraine Prophylaxis
- Aspirin (Low-Dose — Pre-eclampsia Prevention) · Antiplatelet — Pre-eclampsia Prophylaxis
- Palivizumab · RSV Prophylaxis — Monthly Monoclonal Antibody (High-Risk Infants)
- Thiamine (IV/IM — Pabrinex) · Vitamin B1 (Thiamine) — deficiency treatment / Wernicke's encephalopathy prevention
- Ketoconazole (Adrenal Indication) · Adrenal Steroidogenesis Inhibitor (Antifungal with Adrenal Suppressing Properties)
- Doxycycline 100mg Capsules (Sinusitis — Penicillin Allergy) · Tetracycline antibiotic
Pathways
Decision support only — verify against MDCalc, NICE, or your local guideline before clinical use.