About ClinCalc Pro
A clinical reference and decision-support toolkit, built for working clinicians in UK secondary care.
What this is
ClinCalc Pro pulls together validated calculators, drug-dose references, decision pathways and an AI differential generator into one fast, keyboard-friendly interface. Everything is content-driven and rendered statically — pages load in well under a second on mobile data, and the same content is available offline through the Android app.
Validated against MDCalc and primary publications. Every calculator cites its source.
Adult, paediatric and neonatal dosing across 24 specialties. BNF-aligned, with corroborating UK and international guidelines.
Branching decision trees aligned to NICE, ESC, AHA, BTS and equivalent guideline bodies. Source named on every page.
Anthropic Claude Sonnet 4.5 with structured-output prompting. Specialty-aware, pain-severity aware, decision-support only.
How content is sourced
- Calculators
- Formulas reproduced from primary publications and cross-checked against MDCalc. Each calculator links its citation; interpretive thresholds match the published cut-offs.
- Drug doses
- BNF (adult, paediatric, neonatal) is the primary source, with corroboration from NICE TAs/NGs/CKS, MHRA Drug Safety Updates, ESC, ESMO, BSH, BSAC, UKHSA, BHIVA, EASL, RCOG, RCOphth, BAD, NOGG and BSG where applicable. Always verify against your local formulary.
- Pathways
- Branching decision trees aligned to UK and international guidelines (NICE, ESC, AHA, BTS, ATS, GOLD, KDIGO, etc.). The originating guideline is named on every pathway page.
- AI Differential
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Anthropic Claude Sonnet 4.5 (model
claude-sonnet-4-5-20250929) with a structured-output system prompt. Selecting a specialty swaps in a focused lens (e.g. Cardiology: HEART/GRACE, Neurology: NIHSS/ABCD2, Respiratory: Wells/PERC, Psychiatry: MHA/MCA/organic mimics). Pain severity (NRS 0–10) is fed into red-flag and likelihood reasoning. Output is decision-support only.
What this is not
Not a regulated medical device
ClinCalc Pro does not diagnose or treat patients. It assists qualified clinicians by surfacing references, calculations and structured decision support. Final clinical decisions rest with the treating clinician. See the Clinical Disclaimer for full terms.
Limits and data handling
- • No PII storage. The AI Differential proxy receives only the fields you enter. Patient-identifiable information must not be entered. Requests are not logged with content; only IP-level rate-limit counters and aggregate token usage are kept.
- • Rate limits. AI Differential is capped at 5 requests per IP per UTC day, with a global daily cost guardrail.
- • Region. Drug doses and pathways are written for UK secondary-care practice.
Spotted an error?
Wrong dose, missing reference, broken pathway? Tell us — drug-dose corrections in particular are reviewed within 24 hours. See the FAQ for common questions.
Last reviewed: 2026-05-06.