DECAF Score for Acute Exacerbation of COPD
Dyspnoea, Eosinopenia, Consolidation, Acidaemia, and Atrial Fibrillation (DECAF) score predicts in-hospital mortality in acute exacerbations of COPD.
Score interpretation
DECAF 0–1 — in-hospital mortality 1.0% (1.4% in the derivation study).
→ Consider suitability for hospital at home or early supported discharge.
DECAF 2 — in-hospital mortality 5.4% (8.4% in the derivation study).
→ Standard inpatient management; use clinical judgement on place of care.
DECAF 3–6 — in-hospital mortality 21.4% (34.7% in the derivation study).
→ Escalation planning: HDU/ICU review, NIV if hypercapnic acidosis, and discussion of ceilings of care or early palliation.
Interpretation bands for the DECAF Score. Apply clinical judgement and local guidance.
References
- Steer J, Gibson J, Bourke SC. The DECAF Score: predicting hospital mortality in exacerbations of chronic obstructive pulmonary disease. Thorax. 2012;67(11):970–976.
- Echevarria C, Steer J, Heslop-Marshall K, et al. Validation of the DECAF score to predict hospital mortality in acute exacerbations of COPD. Thorax. 2016;71(2):133–140.
Related
Curated clinical cross-links plus same-class fallbacks.
- Azithromycin (COPD Exacerbation Prophylaxis) · Macrolide antibiotic (anti-inflammatory / prophylactic)
- Doxycycline (COPD Exacerbation / CAP) · Oral tetracycline antibiotic
- Co-amoxiclav 625mg (COPD Exacerbation / CAP) · Beta-lactam / Beta-lactamase inhibitor combination antibiotic
- Glyceryl Trinitrate (Sublingual / IV) · Nitrate / Acute Angina
- Dobutamine (Acute HF / Stress Echo) · Inotrope / Acute Heart Failure
- Milrinone · Inodilator / Acute Heart Failure
- Acute Asthma in Adults · BTS/SIGN British Guideline on Asthma 2019; NICE NG80
- Pulmonary Embolism Assessment · NICE NG158; ESC 2019 PE Guidelines
- Acute Exacerbation of COPD (AECOPD) · NICE NG115; GOLD 2024
- Spontaneous Pneumothorax (Adult) · BTS Pleural Disease 2023
- Atypical Pneumonia (Legionella / Mycoplasma / Chlamydophila) · BTS 2023; IDSA
- COPD Exacerbation Management · NICE NG115 / GOLD 2024
Decision support only — verify against a current formulary, NICE, or your local guideline before clinical use.