respiratory anaesthesia-icu

RESP Score for Respiratory ECMO Survival Prediction

Respiratory ECMO Survival Prediction (RESP) score. Predicts in-hospital survival for patients receiving veno-venous ECMO (VV-ECMO) for acute respiratory failure. Based on 12 pre-ECMO variables. Score -22 to +15; Class I (score above 5) = 92% survival; Class V (score below -5) = 18% survival. Developed by Schmidt et al. 2014 from the ELSO registry of 2,355 patients. Used to guide ECMO candidacy decisions.

Age*

Immunocompromised (HIV, post-transplant, chronic immunosuppression, haematological malignancy)*

Mechanical ventilation duration before ECMO*

Primary diagnosis (indication for ECMO)*

CNS dysfunction (hemiparesis/paralysis, CVA, structural intracranial disease, encephalopathy, or seizures)*

Acute kidney injury (creatinine above 133 micromol/L or on dialysis)*

Liver failure (bilirubin above 34 micromol/L or PT above 1.5x control)*

References

Schmidt M et al. Predicting survival after ECMO for refractory cardiogenic shock: the survival after veno-arterial-ECMO (SAVE)-score. Eur Heart J. 2015;36(33):2246-2256.
Schmidt M et al. Predicting survival after extracorporeal membrane oxygenation for severe acute respiratory failure. The Respiratory Extracorporeal Membrane Oxygenation Survival Prediction (RESP) score. Am J Respir Crit Care Med. 2014;189(11):1374-1382.

Curated clinical cross-links plus same-class fallbacks.

Drugs

Pathways

Decision support only — verify against MDCalc, NICE, or your local guideline before clinical use.

References

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