Topical retinoid + antimicrobial
Adapalene with benzoyl peroxide
Brand names: Epiduo
Adult dose
Dose: Apply thin layer to affected area
Route: Topical
Frequency: Once daily in evening
Clinical pearls
- Mild–moderate acne vulgaris; SPF essential; expect 8–12 weeks for response
Contraindications
- Hypersensitivity
Side effects
- Erythema
- Dryness
- Stinging
- Photosensitivity
Interactions
- Other irritants/peroxides
- Bleaches hair/fabric
Monitoring
- Skin tolerance
- Pregnancy avoidance counselling
Reference: BNF; NICE NG198 acne 2021; BAD Acne Guideline; SmPC Epiduo. Verify against your local formulary and the latest BNF before prescribing.
Related
Curated clinical cross-links plus same-class fallbacks.
Pathways
- Suspicious Pigmented Lesion — Melanoma Pathway · NICE NG14 2015 / BAD
- Cellulitis and Erysipelas · NICE NG141 2019 / CREST
- Psoriasis — Severity Assessment and Step-Up Therapy · NICE NG153 2019 / BAD
- Atopic Eczema — Assessment and Step-Up Therapy · NICE NG95 2023
- Urticaria and Angioedema · BSACI / EAACI Guidelines 2022
- Acne Vulgaris — Grading and Treatment · NICE NG198 2021 / BAD