Antipsoriatic / Keratolytic Pregnancy: Caution — theoretical mutagenicity concern; limit use to small areas

Coal Tar

Brand names: Alphosyl HC, Capasal, Clinitar, T/Gel Shampoo

Adult dose

Dose: Apply OD–BD to affected skin. Shampoo: 2–3 times weekly. Coal tar paste: applied to plaques, covered with tubular bandages overnight.

Route: Topical

Frequency: OD–BD (cream/gel); as directed for shampoo/paste

Max: Apply as directed; avoid extensive use on large areas

For psoriasis, seborrhoeic dermatitis, and chronic plaque psoriasis. Stains clothing and bedding. Avoid broken or inflamed skin.

Route: Topical

Frequency: OD–BD

Max: Age-dependent formulation

Concentration: Various concentrations (0.5%–12%) Cream/paste/ml

Safe from birth for seborrhoeic dermatitis (lower concentrations). Higher strengths for older children with plaque psoriasis. Avoid on face.

Renal

N/A

Hepatic

N/A

Staining: advise old clothing and bedding; avoid sun/UV treatment for 24h after application to reduce photosensitivity
NICE NG220: coal tar second-line emollient in psoriasis
Combine with UVB phototherapy in Goeckerman regime for recalcitrant psoriasis
T/Gel shampoo: licensed OTC for seborrhoeic dermatitis and scalp psoriasis

Reference: BNFc; BNF; NICE NG220 Psoriasis; BAD Guidelines. Verify against your local formulary and the latest BNF before prescribing.

Curated clinical cross-links plus same-class fallbacks.

Pathways