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Topical vitamin D analogue

Tacalcitol

Brand names: Curatoderm

Adult dose

Dose: Apply ON to affected skin (max 70g/week)
Route: Topical
Frequency: ON

Clinical pearls

  • Plaque psoriasis — alternative to calcipotriol
  • Avoid face; max 70g/week

Contraindications

  • Hypercalcaemia
  • Pregnancy/breastfeeding (caution)
  • Hypersensitivity

Side effects

  • Skin irritation
  • Hypercalcaemia (extensive use)
  • Photosensitivity

Interactions

  • Other topical preparations (separate)

Reference: BNF; NICE CG153; https://bnf.nice.org.uk/drugs/tacalcitol/. Verify against your local formulary and the latest BNF before prescribing.

Related

Curated clinical cross-links plus same-class fallbacks.