Selective RAR-γ retinoid
Trifarotene
Brand names: Aklief
Adult dose
Dose: Apply 50 micrograms/g cream to affected skin ON
Route: Topical
Frequency: ON
Clinical pearls
- Acne vulgaris (face and trunk)
- Sun protection essential
Contraindications
- Pregnancy/breastfeeding
- Hypersensitivity
Side effects
- Skin irritation
- Photosensitivity
- Sunburn
- Dryness
Interactions
- Other photosensitisers
- Other retinoids
Reference: BNF; NICE NG198; https://bnf.nice.org.uk/drugs/trifarotene/. Verify against your local formulary and the latest BNF before prescribing.
Related
Curated clinical cross-links plus same-class fallbacks.
Pathways
- Suspicious Pigmented Lesion — Melanoma Pathway · NICE NG14 2015 / BAD
- Cellulitis and Erysipelas · NICE NG141 2019 / CREST
- Psoriasis — Severity Assessment and Step-Up Therapy · NICE NG153 2019 / BAD
- Atopic Eczema — Assessment and Step-Up Therapy · NICE NG95 2023
- Urticaria and Angioedema · BSACI / EAACI Guidelines 2022
- Acne Vulgaris — Grading and Treatment · NICE NG198 2021 / BAD