B-vitamin combination

Vitamin B complex

Brand names: Vigantol B-Co

Vitamin B complex preparations combine several water-soluble B vitamins (such as thiamine, riboflavin, niacin, pyridoxine and others) used to prevent or treat deficiency states.

Dosing — not shown for this use

The product information we hold does not support a dose for this page's specific use, route or population, so none is shown. Follow your local or national guideline, and confirm against the product SmPC.

Clinical monograph

How it works

The constituent B vitamins act as essential coenzymes in carbohydrate, protein and fat metabolism and in energy production and nerve function.

Prescribing in practice

Confirm the specific deficiency and choose an appropriate formulation, as high-dose pyridoxine taken chronically can cause peripheral neuropathy.
Water-soluble vitamins are generally well tolerated and excess is largely excreted renally, but the individual constituents should be checked against the indication.
In suspected Wernicke's encephalopathy, parenteral thiamine-containing high-potency preparations are required rather than a standard oral B complex.

Monitoring

Monitoring is primarily clinical, assessing resolution of deficiency symptoms, with biochemical testing reserved for specific deficiencies.

Counselling the patient

Take as directed and do not exceed the recommended intake.
Some products may colour the urine bright yellow, which is harmless.

Evidence & guidelines

B vitamin replacement for deficiency is well established in clinical practice and reflected in UK prescribing references.

Reference: Drug verified in RxNorm (NLM); confirm dosing against the manufacturer SPC (eMC). Verify against your local formulary and current prescribing references before prescribing. Monograph status: clinician-reviewed (2026-07-04).

Curated clinical cross-links plus same-class fallbacks.

Calculators

Pathways