Pneumococcal vaccine (conjugate)
Pneumococcal polysaccharide conjugate vaccine (adsorbed)
Brand names: Prevenar 13, Vaxneuvance, Apexxnar
Adult dose
Dose: 0.5mL IM single dose (PCV13/15/20 per UK schedule); see Green Book
Route: IM
Frequency: per schedule
Clinical pearls
- UK childhood immunisation schedule: PCV13 at 12 weeks and 1 year
- Adults: at-risk groups per Green Book
Contraindications
- Severe hypersensitivity to vaccine components
Side effects
- Injection-site reactions
- Fever
- Irritability (paeds)
- Drowsiness
- Decreased appetite
Interactions
- Immunosuppressives reduce response
- Consider spacing from PPV23
Reference: BNF; UKHSA Green Book Ch.25; https://bnf.nice.org.uk/drugs/pneumococcal-polysaccharide-conjugate-vaccine-adsorbed/. Verify against your local formulary and the latest BNF before prescribing.
Related
Curated clinical cross-links plus same-class fallbacks.