Antioxidant / synthetic ubiquinone analogue
Idebenone
Brand names: Raxone
Adult dose
Dose: 300mg PO TDS with food
Route: PO
Frequency: TDS
Clinical pearls
- Leber's hereditary optic neuropathy (LHON); specialist neuro-ophth service
Contraindications
- Hypersensitivity
Side effects
- GI upset
- Headache
- Backache
Interactions
- BCRP substrates
Monitoring
- Visual acuity
- Colour vision
Reference: BNF; NICE HST7; SmPC; https://bnf.nice.org.uk/drugs/idebenone/. Verify against your local formulary and the latest BNF before prescribing.
Related
Curated clinical cross-links plus same-class fallbacks.
Pathways
- Acute Stroke / TIA Assessment · NICE NG128; RCP Stroke Guidelines 2023
- Status Epilepticus (Adults) · NICE CG137; ESEM guidelines; RCP Neurology Guidelines
- Suspected Subarachnoid Haemorrhage · NICE NG228; RCEM 2023; AHA/ASA 2023
- Adult Head Injury · NICE NG232 (2023)
- Bell's Palsy / Facial Nerve Palsy · ENT UK 2017; AAN
- Vertigo Workup · ENT UK; NICE CKS