Spermicide
Nonoxinol-9
Brand names: Gygel
Adult dose
Dose: Apply per product before intercourse
Route: Vaginal
Frequency: PRN
Clinical pearls
- Used with diaphragm/cap; not recommended as sole contraceptive (failure ~28%/year typical use)
- WHO advises against in HIV-risk populations
Contraindications
- High HIV risk (mucosal irritation increases risk)
- Hypersensitivity
Side effects
- Local irritation
- Mucosal damage
- Allergic reactions
Interactions
- Latex (compatible with most latex condoms; check individual product)
Reference: BNF; FSRH guidance; https://bnf.nice.org.uk/drugs/nonoxinol/. Verify against your local formulary and the latest BNF before prescribing.
Related
Curated clinical cross-links plus same-class fallbacks.