Vaginal DHEA
Prasterone
Brand names: Intrarosa
Adult dose
Dose: 6.5mg pessary intravaginally ON
Route: Vaginal
Frequency: ON
Clinical pearls
- Moderate-severe vulvovaginal atrophy in postmenopausal women
- Local effect; minimal systemic absorption
Contraindications
- Undiagnosed vaginal bleeding
- Hormone-dependent cancer
- Pregnancy
Side effects
- Vaginal discharge
- Abnormal Pap smear
- Weight changes
Interactions
- No clinically significant
Reference: BNF; SmPC; https://bnf.nice.org.uk/drugs/prasterone/. Verify against your local formulary and the latest BNF before prescribing.
Related
Curated clinical cross-links plus same-class fallbacks.