Combined 5-in-1 vaccine
Diphtheria with tetanus, pertussis, poliomyelitis and Hib vaccine
Brand names: Pediacel (legacy)
Adult dose
Dose: 0.5mL IM per schedule
Route: IM
Frequency: Primary schedule
Clinical pearls
- Replaced by 6-in-1 (Infanrix hexa) in UK schedule from 2017
- UKHSA Green Book reference for legacy patients / catch-up
Contraindications
- Anaphylaxis to prior dose
- Encephalopathy
Side effects
- Local reaction
- Fever
- Irritability
Interactions
- Immunosuppressives
Monitoring
- Post-vaccination observation
Reference: BNF; UKHSA Green Book; https://bnf.nice.org.uk/drugs/diphtheria-with-tetanus-pertussis-poliomyelitis-and-haemophilus-influenzae-type-b-vaccine/. Verify against your local formulary and the latest BNF before prescribing.
Related
Curated clinical cross-links plus same-class fallbacks.