Medical-Grade Honey (Manuka)
Brand names: Medihoney, Activon
Medical-grade honey, such as sterilised manuka honey, is a topical wound product used to support debridement and reduce bioburden in a range of acute and chronic wounds, including burns and ulcers.
ClinCalc Pro is rebuilding its dose data from primary open sources — the manufacturer SmPC (eMC), the WHO Model Formulary and other official references — under clinician review. This drug's structured dose is not yet published here. Confirm all doses against the product SmPC and your local formulary before prescribing.
Clinical monograph
How it works
Its wound effects are attributed to high osmolarity, low pH and hydrogen peroxide generation, together with non-peroxide antibacterial activity, which create an environment unfavourable to bacteria and support autolytic debridement.
Prescribing in practice
- Use only sterilised, medical-grade honey products, not culinary honey, to avoid introducing contaminants into the wound.
- Application may cause a transient drawing or stinging sensation, and honey is generally avoided in patients with a known sensitivity to bee products.
- Select dressings and assess wound suitability in line with tissue-viability guidance and current prescribing references.
Monitoring
Review the wound regularly for progress, exudate level and any signs of irritation or infection, adjusting the dressing regimen accordingly.
Counselling the patient
- Explain that this is a sterile medical honey dressing, not food-grade honey.
- Warn that a temporary stinging or drawing sensation can occur after application.
- Advise the patient to report increasing pain, spreading redness or discharge.
Evidence & guidelines
Medical-grade honey is an established option within wound care; selection should follow tissue-viability and current prescribing references rather than substituting culinary honey.
Reference: NICE Evidence Review on Honey Dressings; BBA Wound Care Guidelines; Cochrane Review (Honey as topical treatment for wounds, 2015); Confirm identity and dosing against the manufacturer SPC (eMC) and NICE. Verify against your local formulary and current prescribing references before prescribing. Monograph status: clinician-reviewed (2026-07-04).
Related
Curated clinical cross-links plus same-class fallbacks.