Iron-based phosphate binder
Sucroferric oxyhydroxide
Brand names: Velphoro
Adult dose
Dose: 500mg PO TDS with meals (chewable); titrate to target phosphate
Route: PO
Frequency: TDS with meals
Clinical pearls
- Hyperphosphataemia in CKD on dialysis — alternative to calcium-based binders
- Chew tablets; black stool expected
Contraindications
- Iron overload (haemochromatosis)
- Hypersensitivity
Side effects
- Diarrhoea
- Discoloured stools (black)
- Nausea
- Hyperkalaemia (rare)
Interactions
- Levothyroxine (separate by 4h)
- Doxycycline
- Some antiretrovirals
Monitoring
- Phosphate
- Ferritin
- Calcium
- PTH
Reference: BNF; NICE NG203; https://bnf.nice.org.uk/drugs/sucroferric-oxyhydroxide/. Verify against your local formulary and the latest BNF before prescribing.
Related
Curated clinical cross-links plus same-class fallbacks.
Calculators
- HE-MACS (History and ECG-Based Manchester ACS Risk Score) · ACS Risk Stratification
- Weight-Based Levothyroxine Dose Calculator · Thyroid
- Number Needed to Treat (NNT) / Number Needed to Harm (NNH) · Evidence-Based Medicine
- Corrected Reticulocyte Count / Reticulocyte Production Index · Anaemia
- Ganzoni Equation for Iron Deficiency · Anaemia
- Transferrin Saturation Calculator · Anaemia / Iron Studies