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Short-acting β2-agonist (SABA)

Terbutaline sulfate

Brand names: Bricanyl

Adult dose

Dose: Asthma: 500 micrograms inhaled PRN. Severe: 250–500 micrograms SC/IM. Tocolysis: short-term IV (specialist)
Route: Inhaled/SC/IM/IV
Frequency: PRN

Clinical pearls

  • Asthma reliever (alternative to salbutamol); short-term tocolysis
  • MHRA: short-term tocolytic only ≤48h

Contraindications

  • Hypersensitivity
  • Severe untreated cardiac disease (high-dose)

Side effects

  • Tremor
  • Tachycardia
  • Headache
  • Hypokalaemia
  • Lactic acidosis (high-dose IV)
  • Hyperglycaemia

Interactions

  • β-blockers (avoid)
  • Diuretics (hypokalaemia)
  • Other sympathomimetics

Monitoring

  • K+
  • HR
  • Symptoms

Reference: BNF; BTS/SIGN; MHRA; https://bnf.nice.org.uk/drugs/terbutaline-sulfate/. Verify against your local formulary and the latest BNF before prescribing.

Related

Curated clinical cross-links plus same-class fallbacks.