Vasodilator
Naftidrofuryl oxalate
Brand names: Praxilene
Adult dose
Dose: 100–200mg TDS
Route: PO
Frequency: TDS
Clinical pearls
- Intermittent claudication; first-line oral vasoactive (NICE TA223 / CG147)
- Stop after 3–6 months if no benefit
Contraindications
- Hypersensitivity
- History of hyperoxaluria/calcium oxalate stones
Side effects
- GI upset
- Headache
- Skin rash
- Hepatitis (rare)
Monitoring
- Symptoms, walking distance
Reference: BNF; NICE TA223/CG147; https://bnf.nice.org.uk/drugs/naftidrofuryl-oxalate/. Verify against your local formulary and the latest BNF before prescribing.
Related
Curated clinical cross-links plus same-class fallbacks.
Calculators