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Emergency MedicineHaematologyInfectious Disease

Neutropenic Sepsis

NICE CG151 — neutrophils <0.5 × 10⁹/L (or expected within 24h) + temperature ≥38°C OR signs of sepsis. Antibiotics within 1h of recognition.

Source: NICE CG151; ASCO 2018

Step 1 of ~5
info

Recognise & Resuscitate

Suspect in any cancer patient on chemotherapy (especially within 7–10 days post-cycle). Definition: temp ≥38°C OR signs of sepsis + neutrophils ≤0.5 × 10⁹/L (or anticipated). ABCDE, NEWS2, IV access × 2, monitor. Bloods before antibiotics if no delay.

Related

Curated clinical cross-links plus same-class fallbacks.

Decision support only. Always apply local guidelines and clinical judgement.