AIR Score for Appendicitis
Appendicitis Inflammatory Response (AIR) score — validated tool for stratifying patients with suspected appendicitis. Score 0–12.
Score interpretation
Low risk. Appendicitis unlikely (<5% in low-risk group).
→ Discharge with advice. Return if symptoms worsen. No imaging or admission required.
Intermediate risk. Appendicitis possible (~38% prevalence).
→ Active observation (6–12 hours), serial labs, and CT or ultrasound abdomen. Surgical review.
High risk. Appendicitis highly probable (~85–90%).
→ Surgical review for appendicectomy. CT may be omitted in typical presentations. IV access and pre-op bloods.
Interpretation bands for the AIR Score. Apply clinical judgement and local guidance.
References
- Scott AJ et al. Prospective validation of the appendicitis inflammatory response score: the AIR score is a useful triage tool in patients with suspected appendicitis. Dis Colon Rectum. 2015;58(11):1056-1063.
- de Burlet KJ et al. Prospective validation of the Appendicitis Inflammatory Response score for diagnosis of appendicitis in a New Zealand emergency department. ANZ J Surg. 2015;85(7-8):540-544.
Related
Curated clinical cross-links plus same-class fallbacks.
- Spontaneous Bacterial Peritonitis (SBP) Diagnosis · Diagnostic
- Modified Alvarado Score (MANTRELS) for Appendicitis · Diagnostic
- New Orleans Head CT Decision Rule · Diagnostic
- MS Phenotype Classification (McDonald / Phenotype) · Diagnostic
- CHALICE Rule for Childhood Head Injury · Diagnostic
- STONE Score for Uncomplicated Ureteral Stones · Diagnostic
- Tranexamic Acid (ICU/Trauma/Surgical) · Antifibrinolytic
- Methoxyflurane · Inhaled Analgesic — Acute Pain
- Fentanyl Transdermal Patch (Elderly Chronic Pain) · Opioid Analgesic — Transdermal Patch
- Morphine Slow-Release (Elderly Chronic Pain) · Opioid Analgesic — Modified-Release Oral
- Cefuroxime · Second-Generation Cephalosporin — Respiratory / Surgical Prophylaxis
- Amitriptyline (Neuropathic Pain / Migraine) · Tricyclic Antidepressant / Neuropathic Pain Agent
- Upper GI Bleeding · BSG Guidelines 2019; NICE NG141
- Lower Gastrointestinal Bleed · NICE; BSG; ACPGBI — Commissioning Guide
- Acute Pancreatitis · NICE; IAP/APA; ACPGBI — CG104
- Major Trauma — Primary Survey (ATLS) · ATLS 10th Edition; JRCALC; NICE NG39
- Major Haemorrhage / Massive Transfusion · BCSH; RCOA; RCEM; RCS — BCSH Guidelines
- Burns — TBSA Estimation & Fluid Resuscitation · British Burn Association; EMSB; RCEM 2024
Decision support only — verify against a current formulary, NICE, or your local guideline before clinical use.