ClinCalc Pro
Menu
Calculators Drugs Pathways AI Dx Donate Get the App
Topical NSAID / local analgesic

Benzydamine hydrochloride

Brand names: Difflam

Adult dose

Dose: Mouthwash 15mL gargle/rinse q1.5–3h; oromucosal spray 4–8 sprays q1.5–3h
Route: Topical (oropharyngeal)
Frequency: q1.5–3h

Clinical pearls

  • NICE NG84 sore throat: topical NSAID option for symptomatic relief
  • SACT / ESMO mucositis guidance
  • Available OTC

Contraindications

  • Hypersensitivity

Side effects

  • Local stinging / numbness
  • Hypersensitivity
  • Bronchospasm (aspirin-sensitive asthma)

Interactions

  • Minimal systemic

Monitoring

  • Symptom relief

Reference: BNF; NICE NG84; ESMO mucositis guidance; https://bnf.nice.org.uk/drugs/benzydamine-hydrochloride/. Verify against your local formulary and the latest BNF before prescribing.

Related

Curated clinical cross-links plus same-class fallbacks.

Calculators
Pathways