Antimotility + antiflatulent
Loperamide with simeticone
Brand names: Imodium Plus
Adult dose
Dose: 2 tabs initially, then 1 tab after each loose stool (max 4 tabs/24h OTC)
Route: PO
Frequency: PRN
Clinical pearls
- Acute diarrhoea with bloating/wind
Contraindications
- As loperamide
Side effects
- As loperamide
Interactions
- As loperamide
Reference: BNF; https://bnf.nice.org.uk/drugs/loperamide-with-simeticone/. Verify against your local formulary and the latest BNF before prescribing.
Related
Curated clinical cross-links plus same-class fallbacks.
Calculators
Pathways
- Lower Gastrointestinal Bleed · BSG 2019; NICE NG141
- Variceal Upper GI Bleed · BSG 2015; Baveno VII (2022)
- Spontaneous Bacterial Peritonitis (SBP) · BSG / EASL 2018
- Hepatorenal Syndrome · EASL 2018; ICA 2015
- Hepatic Encephalopathy · EASL 2014; West Haven criteria
- Clostridioides difficile Colitis · NICE NG199 (2021); IDSA/SHEA 2021