GI & Hepatology Drugs

135 drugs

Quick-reference dosing for 135 gi & hepatology medicines, aligned to current UK formularies. Each entry lists adult, paediatric and (where relevant) neonatal doses, renal and hepatic adjustments, contraindications, key interactions, monitoring and clinical pearls — with the source reference. Always confirm doses against current prescribing references before prescribing.

Adalimumab (IBD)

Anti-TNF Monoclonal Antibody
Alginic Acid

Antacid / Alginate (GORD Treatment)
Alverine Citrate

Antispasmodic (Smooth Muscle Relaxant)
Alverine Citrate with Simeticone

Antispasmodic with Antifoaming Agent (Fixed-Dose Combination)
Aprepitant

Antiemetic — Neurokinin 1 (NK₁) Receptor Antagonist
Arachis Oil (Peanut Oil)

Enema (Faecal Softener / Emollient)
Azathioprine

Immunosuppressant
Balsalazide sodium

5-ASA prodrug
Bisacodyl

Stimulant Laxative
Bismuth subcitrate potassium with metronidazole and tetracycline hydrochloride

Quadruple therapy for H. pylori (with PPI)
Bismuth subsalicylate

Bismuth salt (anti-diarrhoeal / antacid)
Budesonide (Oral — IBD)

Topically Acting Corticosteroid
Budesonide (Oral / Rectal)

Corticosteroid — Locally Acting (GI)
Carvedilol (Portal Hypertension)

Non-Selective Beta-Blocker with Alpha₁-Blocking Activity
Chenodeoxycholic acid

Bile acid
Cholic acid

Bile acid replacement
Choline salicylate

Topical analgesic (oral mucosa)
Cimetidine

H2-receptor antagonist
Citric acid

Bowel preparation component
Citric acid with magnesium carbonate

Osmotic bowel cleanser
Co-danthramer

Stimulant + softener laxative
Co-danthrusate

Stimulant + softener laxative
Co-magaldrox (Aluminium and Magnesium Hydroxide)

Antacid
Co-phenotrope

Antimotility (diphenoxylate + atropine)
Colestyramine

Bile acid sequestrant
Colestyramine (Cholestyramine)

Bile Acid Sequestrant / Ion Exchange Resin
Cyclizine

Antiemetic (Antihistamine H₁ Antagonist)
Dicycloverine hydrochloride

Antimuscarinic antispasmodic
Dicycloverine Hydrochloride (Dicyclomine)

Antispasmodic (Anticholinergic)
Dicycloverine hydrochloride with aluminium hydroxide, magnesium oxide and simeticone

Antispasmodic + antacid + antifoaming agent
Docusate sodium

Stool softener (anionic surfactant)
Docusate Sodium

Faecal Softener / Stimulant Laxative
Domperidone

Prokinetic Antiemetic (Peripheral Dopamine Antagonist)
Entecavir

Antiviral — Hepatitis B (Nucleoside Analogue)
Esomeprazole

Proton Pump Inhibitor (PPI)
Etrasimod

Sphingosine-1-phosphate receptor modulator
Famotidine

H₂-Receptor Antagonist
Filgotinib

JAK1 Inhibitor (UC)
Fosaprepitant

NK1 receptor antagonist
Furosemide (Ascites / Cirrhosis)

Loop Diuretic
Gaviscon Advance (Alginate Preparation)

Alginate / Antacid Combination
Glecaprevir / Pibrentasvir

Antiviral — Hepatitis C (Pan-Genotypic DAA)
Glycerol

Stimulant suppository / lubricant
Glycerol phenylbutyrate

Nitrogen-binding agent
Glycerol Suppositories

Stimulant / Osmotic Rectal Laxative
Glycerol with magnesium sulfate and phenol

Topical drawing paste / suppository combo
Granisetron

5-HT3 antagonist antiemetic
Hydrocortisone Acetate Rectal Foam / Enema

Topical Rectal Corticosteroid
Hyoscine Butylbromide

Antispasmodic (Anticholinergic)
Hyoscine hydrobromide

Antimuscarinic
Infliximab

Anti-TNF Monoclonal Antibody
Ispaghula Husk

Bulk-Forming Laxative
Lactulose

Laxative
Lactulose (Hepatic Encephalopathy)

Osmotic Laxative / Ammonia-Reducing Agent
Lansoprazole

Proton Pump Inhibitor (PPI)
Linaclotide

Guanylate cyclase-C agonist
Liquid paraffin

Lubricant
Loperamide hydrochloride

Antimotility opioid
Loperamide Hydrochloride

Antidiarrhoeal (Opioid Receptor Agonist — Peripheral)
Loperamide with simeticone

Antimotility + antiflatulent
Macrogol (Polyethylene Glycol)

Osmotic Laxative
Macrogol 3350

Osmotic laxative
Macrogol 3350 with KCl/NaHCO3/NaCl

Osmotic bowel cleanser
Macrogol 3350 with sulfate, ascorbate, KCl & NaCl (bowel prep)

Osmotic bowel cleanser
Magnesium carbonate

Antacid
Magnesium citrate

Osmotic laxative / bowel-prep component
Magnesium citrate with sodium picosulfate

Stimulant + osmotic bowel cleanser
Magnesium hydroxide

Osmotic laxative / antacid
Magnesium trisilicate

Antacid
Magnesium trisilicate with Mg carbonate & NaHCO3

Antacid
Maralixibat

IBAT (apical sodium-bile acid transporter) inhibitor
Mebeverine hydrochloride

Antispasmodic
Mebeverine Hydrochloride

Antispasmodic (Direct-Acting)
Mebeverine with ispaghula husk

Antispasmodic + bulk-forming laxative
Mercaptopurine (6-MP)

Thiopurine Immunomodulator
Mesalazine (5-Aminosalicylic Acid)

Gastroprotective
Methylnaltrexone bromide

Peripheral μ-opioid receptor antagonist
Metoclopramide

Antiemetic
Metoclopramide hydrochloride

Dopamine D2 antagonist antiemetic / prokinetic
Midodrine

Alpha₁-Adrenergic Agonist (Vasopressor — Oral)
Mirikizumab

Anti-IL-23p19 monoclonal antibody
Nabilone

Synthetic cannabinoid
Naldemedine

Peripheral μ-opioid receptor antagonist
Naloxegol

Peripheral μ-opioid receptor antagonist
Nizatidine

H2-receptor antagonist
Nystatin (Oral Suspension)

Antifungal (Polyene — Topical GI)
Obeticholic Acid

Farnesoid X Receptor (FXR) Agonist
Obeticholic Acid

FXR Agonist (Primary Biliary Cholangitis)
Octreotide

Somatostatin Analogue
Odevixibat

IBAT (apical sodium-bile acid transporter) inhibitor
Olsalazine sodium

5-aminosalicylate
Omeprazole

Gastroprotective
Ondansetron

Antiemetic
Ozanimod

S1P Receptor Modulator (UC)
Palonosetron

Long-acting 5-HT3 antagonist
Palonosetron with netupitant

5-HT3 + NK1 antagonist combo
Pancreatin (Pancreatic Enzyme Replacement Therapy — PERT)

Pancreatic Enzyme Supplement
Pantoprazole

Proton Pump Inhibitor (PPI)
Peppermint Oil

Antispasmodic (Natural — Calcium Channel Blocker in Intestinal Smooth Muscle)
Prednisolone (IBD / GI Use)

Systemic Corticosteroid
Prochlorperazine

Antiemetic (Phenothiazine — Dopamine D₂ Antagonist)
Propranolol (Portal Hypertension)

Antihypertensive
Prucalopride

Selective Serotonin (5-HT₄) Receptor Agonist — Prokinetic
Rabeprazole sodium

Proton pump inhibitor
Rifaximin

Antibiotic
Rifaximin

Non-Absorbable Antibiotic (Hepatic Encephalopathy / IBS-D)
Risankizumab

IL-23 Inhibitor (IBD)
Seladelpar

PPAR-δ agonist
Senna

Stimulant Laxative
Senna with ispaghula husk

Stimulant + bulk-forming laxative combination
Simeticone

Antifoaming agent
Simeticone with aluminium hydroxide and magnesium hydroxide

Antacid + antifoaming
Sodium Acid Phosphate Enema

Osmotic / Stimulant Rectal Laxative
Sodium acid phosphate with sodium bicarbonate

Bowel preparation
Sodium acid phosphate with sodium phosphate

Phosphate enema / oral bowel preparation
Sodium alginate with calcium carbonate and sodium bicarbonate

Reflux suppressant (alginate raft + antacid)
Sodium alginate with potassium bicarbonate

Reflux suppressant (low-sodium)
Sodium Picosulfate

Stimulant Laxative / Bowel Preparation Agent
Sofosbuvir / Velpatasvir

Antiviral — Hepatitis C (Pan-Genotypic DAA)
Sorafenib

Tyrosine Kinase Inhibitor (HCC)
Spironolactone (Ascites / Cirrhosis)

Aldosterone Antagonist / Potassium-Sparing Diuretic
Sterculia

Bulk-forming laxative
Sterculia with frangula

Bulk-forming + stimulant laxative
Sucralfate

Mucosal Protective Agent
Sulfasalazine

Aminosalicylate / Disease-Modifying Antirheumatic Drug (DMARD)
Teduglutide

GLP-2 analogue
Tenofovir (TDF/TAF)

Antiviral — Hepatitis B (Nucleotide Analogue)
Terlipressin

Vasopressin Analogue
Terlipressin acetate

Vasopressin analogue
Tofacitinib

JAK Inhibitor (Janus Kinase 1 and 3 Inhibitor)
Upadacitinib

JAK Inhibitor (IBD)
Urea (13C)

13C-urea breath test
Ursodeoxycholic Acid (UDCA)

Gastroprotective
Ustekinumab

Anti-IL-12/23 Monoclonal Antibody
Vedolizumab

Anti-Integrin Monoclonal Antibody (Gut-Selective)