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Osmotic / Stimulant Rectal Laxative

Sodium Acid Phosphate Enema

Brand names: Fleet Ready-to-Use Enema, Phosphate Enema BP

A sodium acid phosphate enema is a rectally administered phosphate preparation used to produce rapid bowel evacuation, for example before procedures or for constipation.

Dosing — being independently re-sourced

ClinCalc Pro is rebuilding its dose data from primary open sources — the manufacturer SmPC (eMC), the WHO Model Formulary and other official references — under clinician review. This drug's structured dose is not yet published here. Confirm all doses against the product SmPC and your local formulary before prescribing.

Clinical monograph

How it works

Instilled phosphate salts exert an osmotic effect in the rectum and lower bowel, drawing in water and stimulating peristalsis to promote evacuation.

Prescribing in practice

  • Phosphate enemas can cause serious fluid and electrolyte disturbances, so they should be avoided or used with great caution in renal impairment, cardiac disease and frail elderly patients.
  • Careful rectal insertion is needed to avoid local trauma, and they are contraindicated where there is bowel obstruction or perforation.
  • Repeated or retained administration increases the risk of phosphate absorption and electrolyte imbalance.

Monitoring

Monitor for adequate evacuation and, in vulnerable patients, watch for signs of fluid depletion or electrolyte disturbance.

Counselling the patient

  • This is given rectally and usually works within a short time.
  • Tell the clinician if you have kidney or heart problems before it is used.

Evidence & guidelines

Sodium acid phosphate enemas are an established means of rapid bowel evacuation, with documented cautions in UK prescribing references.

Reference: MHRA Safety Alert — Phosphate Enemas in Renal Impairment; SPC Fleet Enema; Confirm identity and dosing against the manufacturer SPC (eMC) and NICE. Verify against your local formulary and current prescribing references before prescribing. Monograph status: clinician-reviewed (2026-07-04).

Related

Curated clinical cross-links plus same-class fallbacks.