Sodium Acid Phosphate Enema

The page's 'Fleet' brand is a different manufacturer's product whose composition is not in this SPC and is not covered. §2 (verbatim): 'Each 128 ml enema contains: Sodium Dihydrogen Phosphate Dihydrate 10% w/v Disodium Phosphate Dodecahydrate 8% w/v'. §4.1 (verbatim): 'Routine treatment of constipation. Pre- and post-operative cleansing of the bowel, in obstetrics and prior to proctoscopy, sigmoidoscopy or X-ray examination.' VERBATIM §4.2: 'Adults, elderly and children over 12 years old: One enema no more than once daily or as directed by a physician (see section 4.4). Children aged 3 years to less than 12 years: As directed by a physician (see sections 4.4 and 4.9). Reduce adult dosage in proportion to body weight. Children under 3 years of age: Fletchers' Phosphate Enema is contraindicated in children under 3 years of age (see section 4.3). Renal impairment Do not administer to patients with clinically significant impairment of renal function (see section 4.3). The product should be used with caution in patients with impaired renal function, when the clinical benefit is expected to outweigh the risk of hyperphosphataemia (see section 4.4). Method of administration For rectal administration only. The enema may be administered at room temperature or warmed in water before use.' The maximum above is the SPC's own wording: 'no more than once daily' (§4.2) and 'Administration of more than one enema in a 24-hour period can be harmful' (§4.4). No paediatric block is written: for ages 3 to under 12 the SPC prints only 'as directed by a physician' / 'reduce adult dosage in proportion to body weight' with no figure, and under 3 years it is contraindicated. §4.4 (verbatim, key limits): 'Unless directed by a physician Fletchers' Phosphate Enema should not be used for more than one week.' 'Repeated and prolonged use ... is not recommended as it may cause habituation.' 'In general, evacuation occurs approximately 5 minutes after sodium phosphate enema administration. Retention time over 10 minutes is not recommended. If evacuation does not occur after using sodium phosphate enema or if the retention time lasts for more than 10 minutes, phosphatemia could occur. No further administrations should be given and the condition of the patient should be assessed by a physician.' 'Do not use ... when nausea, vomiting or abdominal pain is present unless directed by a physician.' 'Care should be taken not to use undue force in administration of the enema especially in the elderly or debilitated patients or those with neurological disorders.' Contains 505 mg benzalkonium chloride per 128 ml enema.