Antifoaming agent
Simeticone
Brand names: Infacol, Wind-eze
Adult dose
Dose: 100–250mg PO with meals + ON. Infants: 0.5–1mL of 40mg/mL before feeds
Route: PO
Frequency: with meals
Clinical pearls
- Infant colic, post-procedural bloating
- Pre-endoscopy/colonoscopy bowel prep adjunct
Contraindications
- Hypersensitivity
Side effects
- Generally well tolerated
Interactions
- No clinically significant
Reference: BNF; NICE CKS; https://bnf.nice.org.uk/drugs/simeticone/. Verify against your local formulary and the latest BNF before prescribing.
Related
Curated clinical cross-links plus same-class fallbacks.
Pathways
- Lower Gastrointestinal Bleed · BSG 2019; NICE NG141
- Variceal Upper GI Bleed · BSG 2015; Baveno VII (2022)
- Spontaneous Bacterial Peritonitis (SBP) · BSG / EASL 2018
- Hepatorenal Syndrome · EASL 2018; ICA 2015
- Hepatic Encephalopathy · EASL 2014; West Haven criteria
- Clostridioides difficile Colitis · NICE NG199 (2021); IDSA/SHEA 2021