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Aminoglycoside antibiotic (topical)

Framycetin sulfate

Brand names: Soframycin

Adult dose

Dose: Eye/ear drops 0.5%: 1–2 drops every 1–2 hours initially, reducing as infection controlled
Route: Topical (eye/ear)
Frequency: varies

Clinical pearls

  • Bacterial conjunctivitis or otitis externa with intact tympanic membrane
  • Limit course to ≤7 days to reduce sensitisation

Contraindications

  • Perforated tympanic membrane (ear)
  • Hypersensitivity to aminoglycosides

Side effects

  • Local hypersensitivity
  • Ototoxicity if extensive use through perforated TM

Reference: BNF; https://bnf.nice.org.uk/drugs/framycetin-sulfate/. Verify against your local formulary and the latest BNF before prescribing.

Related

Curated clinical cross-links plus same-class fallbacks.