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Polyene antifungal

Nystatin

Brand names: Nystan

Adult dose

Dose: Oral candidiasis: 100,000 units (1mL) 4 times/day after food, retain in mouth before swallowing, continue 48h after symptoms resolve
Route: PO/Topical
Frequency: QDS

Paediatric dose

Route: PO
Frequency: QDS
Age bands
  • 0–1m: 100,000 units (1mL) QDS
  • 1–216m: 100,000 units QDS

Clinical pearls

  • Not absorbed systemically — safe in pregnancy/breastfeeding
  • Oral candida in infants and immunocompromised; topical for cutaneous candidiasis

Contraindications

  • Hypersensitivity

Side effects

  • GI upset (rare)
  • Local irritation

Reference: BNFc; BNF; NICE CKS; https://bnf.nice.org.uk/drugs/nystatin/. Verify against your local formulary and the latest BNF before prescribing.

Related

Curated clinical cross-links plus same-class fallbacks.

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