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Live oral attenuated rotavirus vaccine

Rotavirus vaccine

Brand names: Rotarix

Adult dose

Dose: Paediatric only: 1.5mL PO at 8 and 12 weeks
Route: PO
Frequency: x2 doses

Clinical pearls

  • UK childhood immunisation: 8 + 12 weeks; complete by 24 weeks
  • Spit-out doses not repeated

Contraindications

  • Previous intussusception
  • SCID
  • Combined immunodeficiency
  • Age >24 weeks 0 days at first dose
  • Acute severe illness

Side effects

  • Diarrhoea
  • Vomiting
  • Fever
  • Intussusception (small risk — withhold if signs)

Interactions

  • Immunosuppressives
  • Live vaccines (no minimum interval needed)

Reference: BNF; UKHSA Green Book Ch.27b; https://bnf.nice.org.uk/drugs/rotavirus-vaccine/. Verify against your local formulary and the latest BNF before prescribing.

Related

Curated clinical cross-links plus same-class fallbacks.

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