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Medical Device / Topical Scar Treatment

Silicone Gel / Sheeting (Scar Management)

Brand names: Mepiform, Cica-Care, Dermatix, NewGel+E

Silicone gel and silicone sheeting are topical scar-management products used to prevent and improve hypertrophic and keloid scarring following burns, surgery and other wounds.

Dosing — being independently re-sourced

ClinCalc Pro is rebuilding its dose data from primary open sources — the manufacturer SmPC (eMC), the WHO Model Formulary and other official references — under clinician review. This drug's structured dose is not yet published here. Confirm all doses against the product SmPC and your local formulary before prescribing.

Clinical monograph

How it works

Silicone is thought to act mainly by occlusion and hydration of the stratum corneum, normalising the scar microenvironment and modulating fibroblast activity and collagen deposition rather than through any systemic drug action.

Prescribing in practice

  • Apply only to fully healed, closed skin, not to open or broken wounds, to avoid maceration and irritation.
  • Consistent, prolonged daily use over weeks to months is needed for benefit, and skin should be kept clean and dry under sheeting.
  • Select silicone products and timing in line with scar-management and tissue-viability guidance.

Monitoring

Review the maturing scar periodically for colour, height and pliability, and check the underlying skin for irritation or breakdown.

Counselling the patient

  • Explain that silicone is used on healed skin to flatten and soften scars over time.
  • Stress that regular, prolonged use is essential for it to work.
  • Advise stopping and seeking review if the skin becomes irritated or breaks down.

Evidence & guidelines

Silicone gel and sheeting are first-line non-invasive options in international scar-management guidance for preventing and treating hypertrophic and keloid scars.

Reference: British Burns Association Scar Management Guidelines 2019; NICE NG24 (Burns); Mustoe et al. Plast Reconstr Surg 2002 (International Advisory Panel on Scar Management); Confirm identity and dosing against the manufacturer SPC (eMC) and NICE. Verify against your local formulary and current prescribing references before prescribing. Monograph status: clinician-reviewed (2026-07-04).

Related

Curated clinical cross-links plus same-class fallbacks.