ClinCalc Pro
Menu
Long-acting benzodiazepine hypnotic

Flurazepam

Brand names: Dalmane

Adult dose

Dose: 15–30mg at bedtime
Route: PO
Frequency: nocte

Clinical pearls

  • Avoid in elderly — long half-life accumulates
  • Limit to ≤2–4 weeks; melatonin/Z-drugs preferred

Contraindications

  • Severe respiratory disease
  • Sleep apnoea
  • Severe hepatic impairment
  • Myasthenia gravis

Side effects

  • Drowsiness
  • Hangover effect (long t½)
  • Dependence
  • Falls in elderly

Interactions

  • CNS depressants
  • CYP3A4 inhibitors

Reference: BNF; NICE TA77; https://bnf.nice.org.uk/drugs/flurazepam/. Verify against your local formulary and the latest BNF before prescribing.

Related

Curated clinical cross-links plus same-class fallbacks.