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Topical/inhaled corticosteroid

Fluticasone

Brand names: Flixotide, Flixonase, Flutiform, Cutivate

Adult dose

Dose: Asthma inhaled: 100–500 micrograms BD (propionate) or 92–184 micrograms OD-BD (furoate). Nasal: 1–2 sprays OD. Topical (Cutivate): apply OD–BD
Route: Inhaled/Nasal/Topical
Frequency: OD-BD

Clinical pearls

  • Asthma, COPD (with LABA), allergic rhinitis, eczema/psoriasis
  • Rinse mouth after inhaled use

Contraindications

  • Untreated chest infection
  • Local sensitivity

Side effects

  • Oral candidiasis (inhaled)
  • Hoarseness
  • Adrenal suppression at high dose
  • Skin atrophy (topical)
  • Epistaxis (nasal)

Interactions

  • Strong CYP3A4 inhibitors (ritonavir, ketoconazole) — Cushing's reported

Monitoring

  • Symptom control
  • Growth in children

Reference: BNF; BTS/SIGN; NICE NG80/NG115; https://bnf.nice.org.uk/drugs/fluticasone/. Verify against your local formulary and the latest BNF before prescribing.

Related

Curated clinical cross-links plus same-class fallbacks.