haematology
Graded Prognostic Assessment for GI Cancer (GI-GPA)
Graded Prognostic Assessment (GPA) adapted for gastrointestinal cancers with brain metastases. Guides prognosis and treatment decisions (SRS vs WBRT vs palliative). GI-GPA score 0-4: score 0-1.0 = poor prognosis (median survival 3 months); score 3.5-4.0 = best prognosis (median survival 13.5 months). From Sperduto et al. 2012.
References
- Sperduto PW et al. Diagnosis-specific prognostic factors, indexes, and treatment outcomes for patients with newly diagnosed brain metastases: a multi-institutional analysis of 4,259 patients. Int J Radiat Oncol Biol Phys. 2010;77(3):655-661.
- Sperduto CM et al. The graded prognostic assessment for gastrointestinal cancer brain metastases. J Neurooncol. 2012;110(3):447-452.
Related
Curated clinical cross-links plus same-class fallbacks.
Drugs
Pathways
- Major Haemorrhage / Massive Transfusion · BCSH; RCOA; RCEM; RCS — BCSH Guidelines
- Anaemia Investigation · BSH / NICE
- Splenomegaly Workup · BSH; BMJ Best Practice
- Deep Vein Thrombosis Diagnosis and Treatment · NICE CG144 / NICE NG158
- Sickle Cell Crisis · BSH 2021 / BCSH
- Neutropenic Sepsis · NICE CG151 2012 / ESMO
Decision support only — verify against MDCalc, NICE, or your local guideline before clinical use.