haematology
Neutropenic Sepsis
Emergency management of febrile neutropaenia — MASCC score and antibiotic escalation
Source: NICE CG151 2012 / ESMO
Step 1 of ~8
info
Neutropenic Sepsis
Neutrophil count <0.5 × 10⁹/L (or <1.0 and expected to fall) + temp ≥38°C (single episode) or two readings ≥37.5°C 1h apart. Oncology or haematology emergency.
Related
Curated clinical cross-links plus same-class fallbacks.
Drugs
- Piperacillin-Tazobactam (Burns — Sepsis) · Antibiotic — Extended-Spectrum Penicillin + Beta-Lactamase Inhibitor
- Meropenem (Burns — Severe Sepsis/MDR) · Antibiotic — Carbapenem
- Insulin (IV Infusion — ICU Glucose Control) · Insulin — ICU Glucose Management
- Sodium Chloride 3% (Hypertonic Saline) · Hypertonic Electrolyte Solution — ICP/Hyponatraemia Management
- Labetalol (IV — Hypertensive Emergency) · Combined Alpha-1 and Beta-Adrenergic Blocker
- Doxycycline 100mg (Acne / Rosacea) · Oral tetracycline antibiotic (anti-acne / anti-rosacea)
Pathways
- Major Haemorrhage / Massive Transfusion · BCSH; RCOA; RCEM; RCS — BCSH Guidelines
- Anaemia Investigation · BSH / NICE
- Deep Vein Thrombosis Diagnosis and Treatment · NICE CG144 / NICE NG158
- Sickle Cell Crisis · BSH 2021 / BCSH
- Anticoagulation Reversal · BSH 2016 / ESC
- Blood Transfusion — Indications and Safety · BSH 2012 / NICE
Decision support only. Always apply local guidelines and clinical judgement.