Infectious Disease Critical Care Respiratory Medicine B
Clinical Pulmonary Infection Score (CPIS)
Diagnoses ventilator-associated pneumonia (VAP) and hospital-acquired pneumonia (HAP). Score >6 suggests VAP.
Used in: Pneumonia
Score interpretation
VAP Unlikely 0–5
CPIS ≤5: VAP unlikely
→ Consider discontinuing empirical antibiotics; monitor
VAP Likely 6–12
CPIS >6: Consistent with VAP
→ Initiate/continue empirical broad-spectrum antibiotics; send BAL/cultures; follow local VAP protocol
Interpretation bands for the CPIS. Apply clinical judgement and local guidance.
References
- Pugin J, et al. Diagnosis of ventilator-associated pneumonia by bacteriologic analysis of bronchoscopic and nonbronchoscopic 'blind' bronchoalveolar lavage fluid. Am Rev Respir Dis. 1991;143(5 Pt 1):1121-1129.
Related
Curated clinical cross-links plus same-class fallbacks.
Calculators
Drugs
- Nitric Oxide (Inhaled — iNO) · Selective Pulmonary Vasodilator
- Selexipag · Pulmonary Arterial Hypertension
- Macitentan · Pulmonary Arterial Hypertension
- Lefamulin · Pleuromutilin Antibiotic (Community-Acquired Pneumonia)
- Lissamine Green 1% Eye Drops · Vital Dye — Ocular Surface Staining (Dry Eye Diagnosis)
- Ceftriaxone (Paediatric) · Third-Generation Cephalosporin — Meningitis / Sepsis / Community-Acquired Pneumonia
Pathways
- Infective Endocarditis · ESC 2023 Infective Endocarditis Guidelines; NICE NG41
- Eczema Herpeticum · BAD; NICE CKS
- Suspected Bacterial Meningitis (Adult) · NICE NG240 (2024); NICE NG143 (paeds)
- Clostridioides difficile Colitis · NICE NG199 (2021); IDSA/SHEA 2021
- Returning Traveller — Fever · NaTHNaC; PHE; ESCMID 2018
- Malaria — Diagnosis & Management · PHE 2016; WHO 2023
Decision support only — verify against a current formulary, NICE, or your local guideline before clinical use.