Topical otic spray (steroid + acidifier + aminoglycoside)
Dexamethasone with glacial acetic acid and neomycin sulfate
Brand names: Otomize
Adult dose
Dose: 1 metered spray to affected ear TDS
Route: Otic
Frequency: TDS
Clinical pearls
- NICE CKS Otitis externa: option for acute OE
- Acidifier (acetic acid) limits Pseudomonas growth; aminoglycoside cover
- ENT UK
Contraindications
- Perforated tympanic membrane (relative)
- Aminoglycoside hypersensitivity
Side effects
- Local stinging
- Hypersensitivity
- Ototoxicity (perforated drum)
- Superinfection
Interactions
- Other ototoxic drugs
Monitoring
- Symptom resolution
- Ear examination at 7 days
Reference: BNF; NICE CKS Otitis externa; ENT UK; https://bnf.nice.org.uk/drugs/dexamethasone-with-glacial-acetic-acid-and-neomycin-sulfate/. Verify against your local formulary and the latest BNF before prescribing.
Related
Curated clinical cross-links plus same-class fallbacks.
Calculators
- Steroid Dose Equivalence · Medications
- Adrenal Crisis Risk Score · Adrenal Disorders
- Ideal Body Weight (Devine) · Anthropometry
- Lille Model (Steroid Response in Alcoholic Hepatitis) · Alcoholic Liver Disease
- Ho Index for Predicting Response to Medical Therapy in IBD · Inflammatory Bowel Disease
- Apfel Score for Postoperative Nausea and Vomiting · Perioperative