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Stimulant + softener laxative

Co-danthrusate

Brand names: Normax

Adult dose

Dose: 1–3 capsules at bedtime
Route: PO
Frequency: nocte

Clinical pearls

  • Restricted to terminal illness

Contraindications

  • Intestinal obstruction
  • Acute abdomen
  • Colostomy/ileostomy
  • Children <6

Side effects

  • Red urine
  • Perianal skin irritation
  • Carcinogenic in rodents

Reference: BNF; https://bnf.nice.org.uk/drugs/co-danthrusate/. Verify against your local formulary and the latest BNF before prescribing.

Related

Curated clinical cross-links plus same-class fallbacks.