Stimulant + softener laxative
Co-danthramer
Adult dose
Dose: Standard: 1–2 capsules nocte (or 5–10mL suspension). Strong: 1 capsule nocte (or 5mL strong suspension)
Route: PO
Frequency: nocte
Clinical pearls
- Restricted to terminally ill due to rodent carcinogenicity concerns
Contraindications
- Intestinal obstruction
- Acute abdomen
- Colostomy/ileostomy patients
- Children <6 (not licensed)
Side effects
- Red urine discolouration
- Local skin irritation (perianal)
- Carcinogenic in rodents
Reference: BNF; https://bnf.nice.org.uk/drugs/co-danthramer/. Verify against your local formulary and the latest BNF before prescribing.
Related
Curated clinical cross-links plus same-class fallbacks.