Vitamin B12 supplement
Cyanocobalamin
Brand names: Cytacon
Adult dose
Dose: Dietary deficiency: 50–150 micrograms PO OD between meals. (Pernicious anaemia: hydroxocobalamin IM is preferred)
Route: PO/IM
Frequency: OD
Clinical pearls
- Dietary B12 deficiency in vegans/vegetarians
- Use hydroxocobalamin IM for B12 deficiency due to malabsorption
Contraindications
- Hypersensitivity
Side effects
- Rare — itching, rash
Interactions
- No clinically significant
Monitoring
- FBC
- B12 level
- Reticulocyte response
Reference: BNF; NICE CKS; https://bnf.nice.org.uk/drugs/cyanocobalamin/. Verify against your local formulary and the latest BNF before prescribing.
Related
Curated clinical cross-links plus same-class fallbacks.
Pathways
- Major Haemorrhage / Massive Transfusion · BCSH; RCOA; RCEM; RCS — BCSH Guidelines
- Anaemia Investigation · BSH / NICE
- Splenomegaly Workup · BSH; BMJ Best Practice
- Deep Vein Thrombosis Diagnosis and Treatment · NICE CG144 / NICE NG158
- Sickle Cell Crisis · BSH 2021 / BCSH
- Neutropenic Sepsis · NICE CG151 2012 / ESMO