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Anabolic steroid

Oxymetholone

Adult dose

Dose: 1–5 mg/kg/day PO; max 100mg/day

Route: PO

Frequency: OD-divided

Clinical pearls

Aplastic anaemia — specialist haematology; CD3 controlled drug

Contraindications

Pregnancy/breastfeeding
Prostate/breast cancer (males)
Severe hepatic impairment
Hypercalcaemia
Nephrosis

Side effects

Hepatotoxicity (incl. peliosis hepatis, hepatocellular carcinoma)
Virilisation in females
Premature epiphyseal closure (children)
Polycythaemia
Hypercholesterolaemia
Fluid retention

Interactions

Warfarin (raised INR)
Insulin/sulfonylureas (altered glucose)
Hepatotoxic drugs

Monitoring

LFTs
FBC
Lipids
Cholesterol

Reference: BNF; SmPC; https://bnf.nice.org.uk/drugs/oxymetholone/. Verify against your local formulary and the latest BNF before prescribing.

Related

Curated clinical cross-links plus same-class fallbacks.

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