GnRH antagonist
Cetrorelix
Brand names: Cetrotide
Adult dose
Dose: 0.25mg SC OD from day 5–6 of stimulation until day of hCG trigger; or 3mg SC single dose on day 7
Route: SC
Frequency: OD
Clinical pearls
- Prevents premature LH surge during controlled ovarian stimulation in IVF/ART
Contraindications
- Pregnancy
- Breastfeeding
- Severe renal/hepatic impairment
- Postmenopause
Side effects
- Injection site reaction
- Headache
- Nausea
- OHSS
Interactions
- No clinically significant interactions
Reference: BNF; https://bnf.nice.org.uk/drugs/cetrorelix/. Verify against your local formulary and the latest BNF before prescribing.
Related
Curated clinical cross-links plus same-class fallbacks.