Cholinergic agonist (muscarinic)
Bethanechol chloride
Brand names: Myotonine
Adult dose
Dose: 10–25mg TDS–QDS PO
Route: Oral
Frequency: TDS–QDS
Clinical pearls
- NICE NG123 OAB / urinary retention — limited UK use
- Postoperative urinary retention; non-obstructive
- Specialist supervision
Contraindications
- Bowel obstruction
- Bladder outflow obstruction
- Asthma
- Active peptic ulcer
- Recent bowel/bladder surgery
- Hyperthyroidism
- Bradycardia / hypotension
- Hypersensitivity
Side effects
- Cholinergic effects (sweating, lacrimation, salivation, miosis, GI upset, bronchospasm, bradycardia, hypotension)
Interactions
- Other cholinergics
- Anticholinergics (antagonism)
- Beta-blockers (bradycardia)
Monitoring
- Voiding response
- BP
- HR
- Bowel function
Reference: BNF; NICE NG123; BAUS; https://bnf.nice.org.uk/drugs/bethanechol-chloride/. Verify against your local formulary and the latest BNF before prescribing.
Related
Curated clinical cross-links plus same-class fallbacks.