α1 adrenoceptor blocker
Indoramin
Brand names: Doralese
Adult dose
Dose: BPH: 20mg BD, increase by 20mg every 2 weeks (max 100mg/day in divided doses). Hypertension: 25–50mg BD
Route: PO
Frequency: BD
Clinical pearls
- Older agent; tamsulosin/alfuzosin/doxazosin generally preferred for BPH
Contraindications
- Heart failure
- Concurrent MAOI
Side effects
- Sedation (notable)
- Postural hypotension
- Dry mouth
- Weight gain
- Failure of ejaculation
Interactions
- MAOIs
- CNS depressants
- Other antihypertensives
Monitoring
- BP
- HR
Reference: BNF; NICE NG134; https://bnf.nice.org.uk/drugs/indoramin/. Verify against your local formulary and the latest BNF before prescribing.
Related
Curated clinical cross-links plus same-class fallbacks.
Calculators