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Antimuscarinic (quaternary)

Propantheline bromide

Brand names: Pro-Banthine

Adult dose

Dose: 15mg PO TDS + 30mg ON
Route: PO
Frequency: TDS + ON

Clinical pearls

  • Adult enuresis, GI hypermotility, hyperhidrosis
  • Take 1h before food

Contraindications

  • Closed-angle glaucoma
  • GI obstruction
  • Urinary retention
  • Myasthenia gravis

Side effects

  • Anticholinergic effects
  • Tachycardia
  • Constipation
  • Dry mouth

Interactions

  • Other antimuscarinics
  • Antacids

Reference: BNF; https://bnf.nice.org.uk/drugs/propantheline-bromide/. Verify against your local formulary and the latest BNF before prescribing.

Related

Curated clinical cross-links plus same-class fallbacks.